Characterisation of the machinery for the formation of endosome-transport carriers

This Earmarked Scholarship project is aligned with a recently awarded Category 1 research grant. It offers you the opportunity to work with leading researchers and contribute to large projects of national significance.

Supervisor – Associate Professor Rohan

This project aims to investigate the cellular components which generate carriers that transport material between compartments within the cell. The process of sorting proteins and sending them to the right place is a fundamental mechanism critical to understand how individual proteins function as the move around within cells. The generated knowledge about how cells organise themselves through the movement of proteins between endosomal intracellular compartments will provide significant benefits by enhancing our capacity to understand this conserved cellular pathway which ensures the integrity of all cellular processes including signalling, communication, homeostasis and development.

This PhD project will be focused on determining the endosome trafficking machinery essential for the formation of endosome-transport carriers. This will require the development of a panel of CrispR mediated knock-out cell line models that will be used to determine which endosome associated protein trafficking machinery are directly responsible for the formation of sub-types of ETCs.

Preferred educational background

Applications will be judged on a competitive basis taking into account the applicant's previous academic record, publication record, honours and awards, and employment history.

A working knowledge of mammalian cell culture and microscopy would be of benefit to someone working on this project.

The applicant will demonstrate academic achievement in the field(s) of cellular biology and the potential for scholastic success.

A background or knowledge of endosome associated biology is highly desirable.

*The successful candidate must commence by Research Quarter 1, 2022. You should apply at least 3 months prior to the research quarter commencement date. International applicants may need to apply much earlier for visa reasons.

Apply now