Improving patient outcomes through innovative 3D in vitro modelling for phenotypic screening and treatment response

Project opportunity

This Earmarked Scholarship project is aligned with a recently awarded Category 1 research grant. It offers you the opportunity to work with leading researchers and contribute to large projects of national significance.

It is increasingly recognised that there are many pathways to disease. The route taken will significantly influence how the disease manifests, signature that can be used for early detection and the type of treatment that will be effective in treatment. Using the endometrium as a model and studying reproductive disease we are developing complex lab based models from patient stem cells that can be manipulated and studied to identify individual patient differences. By generating these models and understanding their development it will enable the development of new, or targeted drugs to treat human diseases. We are a multidisciplinary team of researchers, who value, a collaborative approach, curiosity. diversity and provide a supportive lab culture for outstanding mentoring, teaching, learning, and research outcomes.

The project can be tailored to the interests and career goals of the student, and can including aims such as

  1. understanding how the alteration in stem cell maturation can contribute to disease process and influence mature tissue behaviour, or
  2. generate temporal and spatial maps of niche environments, how these are influenced by genetics and whether this can improve treatment options for individuals.

Projects may involve techniques such as patient sample processing, organoid culturing, molecular cloning, basic and advanced microscopy, microfluidic generation, spatial transcriptomic and proteomic profiling and dry lab coding based data analysis. This student project will enjoy strong supervision and mentoring from a team of high qualified, multi-disciplinary scientists in a world leading laboratory.

Scholarship value

As a scholarship recipient, you'll receive: 

  • living stipend of $32,192 per annum tax free (2023 rate), indexed annually
  • tuition fees covered
  • single Overseas Student Health Cover (OSHC)

Supervisor

Dr Brett McKinnon

Institute for Molecular Bioscience

Email: b.mckinnon@imb.uq.edu.au

Preferred educational background

Your application will be assessed on a competitive basis.

We take into account your

  • previous academic record
  • publication record
  • honours and awards
  • employment history.

A working knowledge of organoid culture, genetics, stem cells would be of benefit to someone working on this project.

The applicant will demonstrate academic achievement in the field(s) of cell biology and the potential for scholastic success.

A background or knowledge of reproduction is highly desirable.

Latest commencement date

If you are the successful candidate, you must commence by Research Quarter 1, 2024. You should apply at least 3 months prior to the research quarter commencement date.

If you are an international applicant, you may need to apply much earlier for visa requirements.

How to apply

You apply for this project as part of your PhD program application.

View application process