Tuning mitophagy in mitochondrial disease

Project opportunity

This Earmarked Scholarship project is aligned with a recently awarded Category 1 research grant. It offers you the opportunity to work with leading researchers and contribute to large projects of national significance.

Mitophagy levels must be maintained within a critical range for cells to function properly and prevent disease. For example, impaired mitophagy can result in the accumulation of damaged mitochondria and is associated with a variety of diseases, including neurodegenerative diseases like Parkinson’s disease. Likewise, excessive mitophagy can result in mitochondrial depletion in diseases, including FBXL4-associated mitochondrial DNA depletion syndrome, known as MDDS, the focus of this proposal. This project will explore the mechanisms by which cells activate and suppress mitophagy pathways.

Scholarship value

As a scholarship recipient, you'll receive: 

  • living stipend of $32,192 per annum tax free (2023 rate), indexed annually
  • tuition fees covered
  • single Overseas Student Health Cover (OSHC)

Supervisor

Dr Julia Pagan

Faculty of Medicine

Email: j.pagan@uq.edu.au

Preferred educational background

Your application will be assessed on a competitive basis.

We take into account your

  • previous academic record
  • publication record
  • honours and awards
  • employment history.

A working knowledge of cell and molecular biology would be of benefit to someone working on this project.

The applicant will demonstrate academic achievement in the field(s) of cell and molecular biology and the potential for scholastic success.

A background or knowledge of cell biology is highly desirable.

Latest commencement date

If you are the successful candidate, you must commence by Research Quarter 1, 2024. You should apply at least 3 months prior to the research quarter commencement date.

If you are an international applicant, you may need to apply much earlier for visa requirements.

How to apply

You apply for this project as part of your PhD program application.

View application process